Biomimetic HPLC measurements for up to 96 compounds.
We carry out six measurements, lipophilicity at 3pHs, protein and phospholipid binding
We calculate the estimated in vivo parameters from the measured data (volume of distribution, tissue binding, plasma protein binding, drug efficiency
Courses on property based design in drug discovery.
Interactive and practical demonstration of the HPLC based biomimetic property measurements, as well as solubility and permeability.
Physchem/ADME module for Drug Discovery MSc students
Life learning courses for pharmacists
HPLC fundamental courses for analytical scientists
Human serum albumin binding
Lipophilicity at various pHs
Analyzing and visualizing chemically aware physico-chemical and biological data
Model building for prediction of in vivo drug distribution